Gene interactions and pathways from curated databases and text-mining

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GCSAM — IL6

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: GCSAM → IL6 (increases, IL6 Translocation)
    Evidence: We demonstrate that IL-6 induces the phosphorylation of the C-terminal tyrosine residue of the HGAL protein via the Lyn kinase, and promotes its relocalization from the cytoplasm to podosome-like structures.
  • OpenBEL Selventa BEL large corpus: GCSAM → IL6 (increases)
    Evidence: We demonstrate that IL-6 induces the phosphorylation of the C-terminal tyrosine residue of the HGAL protein via the Lyn kinase, and promotes its relocalization from the cytoplasm to podosome-like structures.