Rothlin et al., Cell 2007
(Inflammation) :
TLR induction of IFNAR-STAT1 signaling upregulates the TAM system, which in turn usurps the IFNAR-STAT1 cassette to induce the cytokine and TLR suppressors SOCS1 and SOCS3
Green et al., J Immunol 2009
:
In comparison to wild-type B cells, TLR7 stimulated IFNAR ( -/- ) B cells proliferated significantly less well and did not up-regulate costimulatory molecules