◀ Back to HRAS

HRAS — MMP14

Text-mined interactions from Literome

Kim et al., J Biochem Mol Biol 2007 : Membrane-type (MT)1-MMP and tissue inhibitor of metalloproteinase ( TIMP ) -2 were up-regulated by H-Ras but not by N-Ras in the type I collagen coated gel, suggesting that H-Ras-specific up-regulation of MT1-MMP and TIMP-2 may lead to the activation of pro-MMP-2
Yoshida et al., J Virol 2008 (Cell Transformation, Neoplastic...) : This invasiveness resulted from the upregulation of MT1-MMP and MMP9 by H-ras and E7, respectively, in which the activation of the MEK/extracellular signal regulated kinase pathway was involved
Kang et al., Oncol Rep 2009 (Breast Neoplasms...) : Taken together, this study clearly demonstrated the inhibitory effect of simvastatin and lovastatin on H-Ras induced invasion, MMP expression and signal transduction in MCF10A breast epithelial cells, providing supporting rationale for future statin trials as a therapeutic intervention to regulate breast cancer metastasis
Liao et al., Mol Med 2012 (Neoplasm Metastasis...) : CSE1L overexpression also triggered microvesicle generation, and CSE1L knockdown diminished v-H-Ras induced microvesicle generation, matrix metalloproteinase (MMP)-2 and MMP-9 secretion and metastasis of B16F10 melanoma cells