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CTTN — ECM1

Text-mined interactions from Literome

Webb et al., Eur J Cell Biol 2007 (Cell Transformation, Neoplastic...) : We used a short interference RNA/rescue strategy to investigate the role of cortactin in the formation of Src induced invadopodia in 3T3 fibroblasts, and subsequent degradation of the ECM ... These results also suggest that cortactin plays a different role in invadopodia dependent ECM degradation and lamellipodia formation in cell movement
Clark et al., Cancer Res 2007 (Carcinoma, Squamous Cell...) : In the reverse experiment, overexpression of cortactin dramatically increased ECM degradation, far above and beyond the effect on formation of actin/Arp3 positive invadopodia puncta