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CALM2 — RYR1

Text-mined interactions from Literome

Damiani et al., J Muscle Res Cell Motil 2000 : Pharmacological clues to calmodulin mediated activation of skeletal ryanodine receptor using [ 3H ] -ryanodine binding
Rodney et al., Biochemistry 2000 : Regulation of RYR1 activity by Ca ( 2+ ) and calmodulin ... We demonstrate that Ca ( 2+ ) -free calmodulin enhances the affinity of RYR1 for Ca ( 2+ ) while Ca ( 2+ ) binding to calmodulin converts calmodulin from an activator to an inhibitor
Rodney et al., J Biol Chem 2001 : The skeletal muscle calcium release channel , ryanodine receptor, is activated by calcium-free calmodulin and inhibited by calcium bound calmodulin ... This region of the ryanodine receptor has previously been identified as a site of intersubunit contact, suggesting the possibility that calmodulin regulates ryanodine receptor activity by regulating subunit-subunit interactions
Zhao et al., J Biol Chem 2001 : Dantrolene inhibition of the RYR1 was dependent on the presence of the adenine nucleotide and calmodulin and reflected a selective decrease in the apparent affinity of RYR1 activation sites for Ca ( 2+ ) relative to Mg ( 2+ )
Rodney et al., Biochemistry 2001 : Calcium and calmodulin both regulate the skeletal muscle calcium release channel , also known as the ryanodine receptor, RYR1 ... Ca ( 2+ ) -free calmodulin ( apocalmodulin ) activates and Ca ( 2+ ) -calmodulin inhibits the ryanodine receptor
Hill et al., Mol Pharmacol 2004 : Functional regulation of the cardiac ryanodine receptor by suramin and calmodulin involves multiple binding sites
Wolner et al., Br J Pharmacol 2005 (Calcium Signaling...) : As calmodulin activates and inhibits the ryanodine receptor depending on whether Ca2+ is absent or present, suramin analogues were screened for inhibition of the ryanodine receptor
Prosser et al., Cell Calcium 2011 : S100A1 and calmodulin regulation of ryanodine receptor in striated muscle
Lee et al., Nature 1994 : Cyclic ADP ribose activation of the ryanodine receptor is mediated by calmodulin
Dulhunty et al., Acta Physiol Scand 1996 : Effects of phosphorylation, calmodulin , triadin, calsequestrin and interactions with the alpha 1 subunit of the dihydropyridine receptor on ryanodine receptor activity are summarized