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APOB — MAP2K1

Text-mined interactions from Literome

Yang et al., Cell Signal 2000 : Furthermore, we also showed that overexpression of dominant negative mutants of Ras ( RasN17 ) and Raf ( Raf-301 ) completely suppressed MEK1/2 and p42/p44 MAPK activation induced by OX-LDL and PDGF-BB, indicating that Ras and Raf may be required for activation of these kinases
Yang et al., Br J Pharmacol 2001 (MAP Kinase Signaling System) : 7. Overexpression of dominant negative mutants of Ras ( H-Ras-15A ) and Raf ( Raf-N4 ) significantly suppressed MEK1/2 and p42/p44 MAPK activation induced by OX-LDL and PDGF-BB, indicating that Ras and Raf may be required for activation of these kinases
Allister et al., Diabetes 2005 : Inhibition of MEK1/2 significantly attenuated both the naringenin- and insulin induced decrease in apoB100 secretion demonstrating a direct link between MAPK ( erk ) activation and apoB100 secretion