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CD55 — TNF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CD55 → TNF (increases) Varsano et al., Am J Respir Cell Mol Biol 1998*
  Evidence: Modified assertion
• OpenBEL Selventa BEL large corpus: CD55 → TNF (increases) Varsano et al., Am J Respir Cell Mol Biol 1998*
  Evidence: TNF-alpha alone had a consistent time-dependent upregulatory effect on DAF expression, but in combination with IL-1 alpha it showed higher expression levels in both the cells.

Text-mined interactions from Literome

Mason et al., Blood 1999 : Tumor necrosis factor alpha (TNFalpha) and interferon gamma (IFNgamma) each increased DAF expression but not CD59 or MCP expression, and a combination of these cytokines was more potent than either alone
Varsano et al., Thorax 2000 : Interferon (IFN)-gamma ( 10 U/ml/72 h ) and TNF-alpha ( 1000 U/ml/72 h ) increased DAF expression up to a mean of 116 % and 45 %, respectively, above that in unstimulated cells
Halme et al., Mol Immunol 2009 (Hepatitis) : A low basal expression of CD55 was strongly enhanced by IFN-gamma, IL-1 beta and TNF-alpha
Mahtout et al., FEMS Immunol Med Microbiol 2011 : Although these two cytokines had no effect on CD46 and CD55 gene expression in epithelial cells, IL-1ß and tumor necrosis factor-a induced a significant upregulation
Bjørge et al., Cancer Immunol Immunother 1996 (Adenocarcinoma...) : The expression and function of DAF were enhanced by tumour necrosis factor alpha (TNF alpha) and interleukin-1 beta (IL-1 beta)
Andoh et al., Immunology 1997 : In this study, we examined the effects of tumour necrosis factor (TNF)-alpha on DAF expression in three intestinal epithelial cell lines ... In HT-29 cells, the effects of TNF-a on DAF mRNA accumulation were observed in a dose dependent manner ; DAF mRNA accumulation reached a maximum at 3-6 hr, and then gradually decreased ... Messenger RNA stability studies suggested that TNF-alpha partially regulated DAF gene expression by a posttranscriptional mechanism ... In human intestinal epithelial cells, TNF-alpha acts as a potent inducer of DAF mRNA expression, indicating an important role for TNF-alpha in the regulation of DAF expression at the inflamed mucosa
Varsano et al., Am J Respir Cell Mol Biol 1998 (Lung Neoplasms) : In ChaGo K-1 and NCI-H596 lung cancer cell lines, IL-1alpha and TNF-alpha increased DAF expression ... TNF-alpha ( 1, 000 U/ml/72 h ) increased DAF expression up to a mean of 131 and 46 %, respectively