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CD8A — RPL17

Text-mined interactions from Literome

Keir et al., J Immunol 2007 : We tested the role of PD-1 : PD-1 ligand (PD-L) interactions in cross-presentation and the generation and control of CD8 ( + ) responses against self-Ag ... Loss of PD-1 affected CD8 ( + ) cells intrinsically, and did not significantly alter the responses of wild-type OT-I T cells adoptively transferred into the same RIP-ova ( high ) recipient mouse
Zhang et al., J Immunol 2008 (Acute Disease...) : In this study, we observed that CMV-specific CD8 ( + ) T cells displayed numerical decline and functional impairment in the early phase of acute infection, whereas programmed death-1 (PD-1) expression was significantly up-regulated by these CMV-specific CD8 ( + ) T cells
Fourcade et al., J Immunol 2009 (Melanoma) : To investigate the role of PD-1 in impairing spontaneous tumor Ag-specific CD8 ( + ) T cells in melanoma patients, we have examined the effect of PD-1 expression on ex vivo detectable CD8 ( + ) T cells specific to the tumor Ag NY-ESO-1 ... To investigate the role of PD-1 in impairing spontaneous tumor Ag-specific CD8 ( + ) T cells in melanoma patients, we have examined the effect of PD-1 expression on ex vivo detectable CD8 ( + ) T cells specific to the tumor Ag NY-ESO-1 ... In contrast to EBV, influenza, or Melan-A/MART-1-specific CD8 ( + ) T cells, NY-ESO-1-specific CD8 ( + ) T cells up-regulated PD-1 expression
Zhang et al., J Hepatol 2009 (Acute Disease...) : The association between PD-1 expression and HBV-specific memory CD8 T-cell responses were longitudinally analyzed in eighteen patients with acute hepatitis B virus ( HBV ) infection, including ten patients with human leucocyte antigen (HLA)-A201 and eight with other HLA-A2 subtypes
Xu et al., Zhonghua Yi Xue Za Zhi 2009 (Hepatitis B) : Programmed death-1 (PD-1) up-regulation can impair virus-specific CD8 ( + ) T-cell responses during chronic viral infection
Zhou et al., Blood 2010 (Leukemia, Myeloid, Acute) : In vitro, intact Treg suppression of CD8 ( + ) T-cell responses was dependent on PD-1 expression by T cells and Tregs and PD-L1 expression by antigen presenting cells
Vali et al., Eur J Immunol 2010 (Disease Progression...) : Blocking Tim-3 or PD-1 pathways restored both HIV- and HCV-specific CD8 ( + ) T-cell expansion in the blood of co-infected individuals
Gaudreau et al., Cell Immunol 2010 (Diabetes Mellitus) : In addition, LPS stimulated GM.BMDCs possessed a reduced capacity to activate diabetogenic CD8 ( + ) T cells in a PD-1/PD-L1 dependent manner
Lucas et al., Blood 2011 : In contrast, adoptive transfer studies revealed a CD8 T cell-intrinsic requirement for CTLA4/B7.1/B7.2 and for PD-1 for CD8 T-cell tolerance induction