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JUN — UTP6
Text-mined interactions from Literome
Ekokoski et al., J Cell Physiol 2001
:
ATP,
UTP , UDP and ATPgammaS
increased ( 3 ) H-thymidine incorporation into DNA and expression of the protooncogenes c-Fos and
c-Jun , while 2-MeSATP was ineffective, and alpha, beta-meATP gave a response only at 100-microM dose
Huwiler et al., Br J Pharmacol 1997
:
Here we show that ATP and
UTP potently
stimulate the stress activated protein kinase pathway and phosphorylation of the transcription factor
c-Jun ... 4. Down-regulation of protein kinase C-alpha, -delta and -epsilon isoenzymes by 24 h treatment of the cells with 12-O-tetradecanoylphorbol 13-acetate did not inhibit ATP- and
UTP induced activation of
c-Jun phosphorylation ... 5. Pretreatment of the cells with pertussis toxin or the tyrosine kinase inhibitor, genistein, strongly attenuated ATP- and
UTP induced
c-Jun phosphorylation