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PIK3CA — SLPI
Text-mined interactions from Literome
Lee et al., Bone 2010
:
In addition, BMP2 induced beta-Catenin activity and
ALP activity were
blocked by
PI3K inhibition
Mason et al., IDrugs 2010
(Neoplasms) :
This conference report highlights selected presentations on preclinical data on the novel
pan-PI3K pyrimidine derived inhibitor BKM-120 ( Novartis AG ), the dual
inhibition of
mTOR/PI3K in NSCLC by PF-4691502 ( Pfizer Inc ), the small-molecule PDK-1 inhibitors PF-05177624 and PF-05197281 ( both Pfizer ) and the ability of RO-5323441 ( F Hoffmann-La Roche Ltd/ThromboGenics NV/BioInvent International AB ) to block tumor growth in vivo