Matsuzaki et al., Proc Natl Acad Sci U S A 2010
(Ovarian Neoplasms) :
Expression of LAG-3 and PD-1 on CD8 ( + ) T cells was up-regulated by IL-10, IL-6 ( cytokines found in tumor ascites ), and tumor derived antigen presenting cells
Peña-Cruz et al., J Invest Dermatol 2010
:
PD-1 engagement on iLCs reduced IL-6 and macrophage inflammatory protein (MIP)-1alpha cytokine production in response to TLR2 signals but had no effect on LC maturation
Ma et al., Immunology 2011
(Hepatitis C, Chronic) :
PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection