Gene interactions and pathways from curated databases and text-mining

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CAV1 — PTRF

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Hill et al., Cell 2008 : We conclude that PTRF-Cavin is required for caveola formation and sequestration of mobile caveolin into immobile caveolae
Shakirova et al., Eur J Pharmacol 2009 : In KO mice, caveolin-1 was absent, and the expression of the caveola associated protein PTRF-Cavin was reduced
Joshi et al., J Cell Biol 2012 (Breast Neoplasms...) : Cav1 phosphorylation reduces Egr1 binding to Cav1 and cavin-1 promoters and stimulates their activity ... In MDA-231 breast carcinoma cells that express elevated levels of Cav1 and caveolae, Egr1 regulated Cav1, and cavin-1 promoter activity was dependent on actin, Cav1 , Src, and Rho associated kinase as well as downstream protein kinase C ( PKC ) signaling