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NFKBIB — NOS2

Text-mined interactions from Literome

Wang et al., Br J Pharmacol 1999 (Brain Neoplasms...) : Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes
Stasiolek et al., J Biol Chem 2000 (Astrocytoma...) : Expression of full-length rat IkappaB-beta , but not a carboxyl-terminal truncated form, inhibited NOS2 induction and potentiation by lactacystin ... These results suggest that IkappaB-beta contributes to persistent NFkappaB activation and NOS2 expression in glial cells, that IkappaB-beta is a stress protein inducible by hyperthermia or proteasome inhibitors, and that delayed addition of proteasome inhibitors can have stimulatory rather than inhibitory actions