Gene interactions and pathways from curated databases and text-mining

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CCL4 — NOS2

Text-mined interactions from Literome

Rao et al., Indian J Exp Biol 2001 : Fructose, 1,6-diphosphate mitigates CCl4 suppressed nitric oxide synthase activity in rats
Ibrahim et al., Jpn J Vet Res 2008 (Carbon Tetrachloride Poisoning) : Moreover, CCl4 increased iNOS and TNFalpha mRNA, while N. sativa oil administration for one week prior to CCl4 injection downregulated the CCl4 induced iNOS mRNA and up-regulated IL-10 mRNA
Chandrasekar et al., J Infect Dis 2013 (Salmonella Infections, Animal) : Regulation of chemokines, CCL3 and CCL4 , by interferon ? and nitric oxide synthase 2 in mouse macrophages and during Salmonella enterica serovar typhimurium infection ... In this study, the repression of CCL3 and CCL4 by IFN-? and nitric oxide synthase 2 (NOS2) in macrophages and upon Salmonella typhimurium infection of mice was investigated ... Also, during intracellular replication of S. typhimurium in BMDMs, IFN-? and NOS2 repressed CCL3 and CCL4 production ... The physiological roles of these observations were revealed during oral infection of mice with S. typhimurium, wherein endogenous IFN-? and NOS2 enhanced serum amounts of tumor necrosis factor a and CXCL10 but repressed CCL3 and CCL4