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IL8 — NOD1

Text-mined interactions from Literome

Uehara et al., Cell Microbiol 2005 : Muramyldipeptide and diaminopimelic acid containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1 dependent manner, respectively, in human monocytic cells in culture ... Suppression of the mRNA expression of nucleotide binding oligomerization domain ( NOD)1 and NOD2 by RNA interference specifically inhibited the synergistic IL-8 secretion induced by DMP and MDP with these TLR agonists respectively
Opitz et al., J Immunol 2006 : Finally, L. monocytogenes- and Nod1 induced IL-8 production was blocked by a specific p38 inhibitor
Masumoto et al., J Exp Med 2006 : Nod1 stimulation did not induce TNFalpha, interleukin 12, and interferon gamma, suggesting that the primary role of Nod1 is to induce the recruitment of immune cells
Takada et al., Curr Pharm Des 2006 : In human monocytic cells, both MDP and DMPs exhibited definite activities ; marked synergistic interleukin (IL)-8 secretion was induced by DMPs and MDP in combination with synthetic TLR agonists, and suppression of the mRNA expressions of NOD1 and NOD2, respectively, by RNA interference specifically inhibited synergistic IL-8 secretion
da Silva Correia et al., Cell Death Differ 2007 (Breast Neoplasms) : In contrast, several lines of evidence show that Nod1 dependent JNK activation and IL-8 production did not require the presence of caspase 8 but required activation of TAK1 as well as RIP2
Uehara et al., Mol Immunol 2007 : Anti-RP3 Abs markedly promoted the release of IL-8 induced by chemically synthesized TLR and NOD ligands mimicking bacterial components : TLR2-agonistic lipopeptide ( FSL-1 ), TLR3-agonistic poly I:C, TLR4-agonistic lipid A ( LA-15-PP ), TLR7/8-agonistic single stranded RNA ( ssPolyU ), TLR9-agonistic bacterial CpG DNA, NOD1-agonistic FK156/565 and NOD2-agonistic muramyldipeptide ( MDP ) in THP-1 cells and human peripheral blood mononuclear cells, although sole incubation with anti-PR3 Abs induced only a low level of IL-8
Buchholz et al., Infect Immun 2008 (Inflammation) : The cytosolic pattern recognition receptor NOD1 induces inflammatory interleukin-8 during Chlamydia trachomatis infection ... IL-8 induced at 30 h postinfection by C. trachomatis was dependent on NOD1 signaling through RIP2 ; however, the IL-8 response was independent of MyD88 dependent TLR signaling ... We conclude that the endogenous IL-8 response induced by C. trachomatis infection is dependent upon NOD1 PRR signaling through RIP2 as part of a signal system requiring multiple inputs for optimal IL-8 induction
Cho et al., Microb Pathog 2010 : These changes in IL-1beta, IL-6, IL-8 , and ICAM-1 induced by NOD1 knockdown were reversed as the result of IL-32 treatment
Bhavsar et al., PLoS Pathog 2013 : In mammalian cell culture, SspH2 significantly enhanced Nod1 mediated IL-8 secretion when transiently expressed or bacterially delivered
Swain et al., J Biosci 2013 (Bacterial Infections) : In response to both Gram positive and Gram negative bacterial infections, NOD1 and NOD2 receptors signalling were activated and IL-1 beta, IL-8 and IFN- gamma were induced