Gene interactions and pathways from curated databases and text-mining

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IL8 — JAK3

Text-mined interactions from Literome

To et al., Br J Cancer 2004 (Cell Transformation, Neoplastic...) : The interleukin mediated Janus kinase ( JAK ) /STAT pathway plays a crucial role in carcinogenesis
Henkels et al., FEBS Lett 2011 : IL-8 induced a time- and concentration dependent activation of JAK3 activity in neutrophils and differentiated HL-60 leukemic cells ... JAK3 was more robustly activated by IL-8 than other kinases : p70S6K, mTOR, MAPK or PKC