Matsunaga-Udagawa et al., J Biol Chem 2010
:
Shoc2/SUR-8 positively regulates Ras/ERK MAP kinase signaling by serving as a scaffold for Ras and Raf
Galperin et al., PloS one 2012
(MAP Kinase Signaling System) :
To elucidate the mechanism by which Shoc2 regulates ERK1/2 activation by the epidermal growth factor (EGF) receptor ( EGFR ), we studied subcellular localization of Shoc2