Gene interactions and pathways from curated databases and text-mining

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CSF2 — IL1R1

Text-mined interactions from Literome

Lukens et al., J Immunol 2012 (Encephalomyelitis, Autoimmune, Experimental) : Our work demonstrates that IL-1R is required for GM-CSF production after both TCR- and cytokine induced stimulation of immune cells in vitro ... Moreover, secretion of GM-CSF was dependent on IL-1R under both IL-12- and IL-23 induced stimulatory conditions
Groves et al., J Immunol 1995 : At the level of function, gene expression of the IL-1-inducible cytokine granulocyte-macrophage-CSF by keratinocytes was mediated entirely by low numbers of type 1 IL-1R , although type 2 IL-1R were more numerous on both resting and activated keratinocytes
Bruserud et al., Eur J Haematol 1996 (Acute-Phase Reaction...) : IL1RA release from AML blasts was also increased by stem cell factor, tumour necrosis factor alpha (TNF alpha), granulocyte-macrophage colony stimulating factor and macrophage colony stimulating factor, whereas interleukin 3, interleukin 6, leukaemia inhibitory factor and granulocyte colony stimulating factor did not significantly alter IL1RA release