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CDC27 — FBXO5

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CDC27 — FBXO5 (physical association, affinity chromatography technology) Moshe et al., J Biol Chem 2011*
• IRef Biogrid Interaction: CDC27 — FBXO5 (physical association, affinity chromatography technology) Miller et al., Genes Dev 2006
• IRef Biogrid Interaction: CDC27 — FBXO5 (direct interaction, pull down) Miller et al., Genes Dev 2006
• IRef Intact Interaction: Complex of 22 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 21 proteins (association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 23 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification) Hutchins et al., Science 2010
• IRef Intact Interaction: FBXO5 — CDC27 (physical association, anti bait coimmunoprecipitation) Iwai et al., Cell 2007*
• IRef Intact Interaction: Complex of FZR1-FBXO5-CDC27 (association, anti bait coimmunoprecipitation) Bassermann et al., Cell 2008
• IRef Intact Interaction: Complex of 19 proteins (association, tandem affinity purification) Hutchins et al., Science 2010

Text-mined interactions from Literome

Moshe et al., Proc Natl Acad Sci U S A 2004 : Role of Polo-like kinase in the degradation of early mitotic inhibitor 1 , a regulator of the anaphase promoting complex/cyclosome ... Early mitotic inhibitor 1 (Emi1) inhibits the activity of the anaphase promoting complex/cyclosome ( APC/C ), which is a multisubunit ubiquitin ligase that targets mitotic regulators for degradation in exit from mitosis
Marangos et al., J Cell Biol 2007 : In mouse oocytes, we find that early mitotic inhibitor 1 (Emi1) , an inhibitor of the anaphase promoting complex (APC) that is responsible for cyclin B destruction and inactivation of MPF, is present at prophase I and undergoes Skp1-Cul1-F-box/betaTrCP mediated destruction immediately after germinal vesicle breakdown ( GVBD )
Zhang et al., Development 2008 : We identify the mutation as being in early mitotic inhibitor 1 (emi1) , a negative regulator of the Anaphase Promoting Complex , and use the mutant to examine the role of the cell cycle in somitogenesis