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AKT2 — PTP4A3
Text-mined interactions from Literome
Wang et al., Cancer Res 2007
(Colorectal Neoplasms) :
In these cells,
PRL-3 activates
Akt and inactivates glycogen synthase kinase-3beta as assessed by phosphospecific antibodies
Wang et al., Cancer Cell 2010
(Lymphatic Metastasis...) :
Overexpression of PCBP1 inhibits PRL-3 expression and inactivates AKT, whereas knockdown of PCBP1 causes upregulation of
PRL-3 protein levels,
activation of
AKT , and promotion of tumorigenesis
Jiang et al., Cancer Res 2011
(Colonic Neoplasms) :
PRL-3 activation
stimulated PI3K/AKT signaling that caused resistance to stress induced apoptosis