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ARG1 — IL10
Text-mined interactions from Literome
Witte et al., J Surg Res 2002
:
The
effect of transforming growth factor beta1 ( TGF-beta1 ),
interleukin-4 (IL-4), lipopolysaccharide, and wound fluid on
arginase activity was also investigated
Barksdale et al., Surgery 2004
:
Although isoproterenol, IL-4,
IL-10 , and IL-13 individually
induced arginase , significant synergy between the combination of isoproterenol with either TGF-beta or the TH2 cytokines was observed
Bonaparte et al., Glia 2006
(Central Nervous System Viral Diseases) :
Further, both constitutive and
IL-4/IL-10 induced expression of
arginase I correlated with elevated STAT6 nuclear binding activity, decreased NO production, and increased virus replication in motheaten compared to wild type astrocytes
Holán et al., Transplantation 2006
:
Rejection of rat skin xenografts, on the contrary to rejection of allografts, was associated with a local high production of Th2 cytokines IL-4 and
IL-10 , overexpression of arginase genes, strongly
enhanced arginase activity and attenuated NO generation in the graft
Stempin et al., J Biomed Biotechnol 2010
(Parasitic Diseases) :
Arginase-1 can also be
induced by
IL-10 and transforming growth factor-beta ( TGF-beta ) or even directly by parasites or parasite components
Arora et al., Mucosal Immunol 2010
(Eosinophilia...) :
Suppression of Th2 effector function was reversed by
anti-interleukin-10 (IL-10) or
inhibition of
arginase 1
He et al., Am J Pathol 2013
(Choroidal Neovascularization...) :
Targeted ablation of macrophages inhibits the formation of this fibrovascular scaffold, and expression analysis reveals that these macrophages are
Arg1 ( + ) YM1 ( + ) F4/80 ( + ) alternatively activated M2-like macrophages, which do not
require IL-4/STAT6 or
IL-10 signaling for their activation
Corraliza et al., Biochim Biophys Acta 1997
:
Moreover,
interleukin 10 which
induces arginase in macrophages is able to increase the cAMP dependent protein kinase A activity ... Moreover,
interleukin 10 which
induces arginase in macrophages is able to increase the cAMP dependent protein kinase A activity