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WNT10B — WNT2
Text-mined interactions from Literome
Ross et al., Science 2000
:
Here we show that
Wnt signaling, likely
mediated by
Wnt-10b , is a molecular switch that governs adipogenesis
Longo et al., J Biol Chem 2004
(Body Weight) :
Activation of canonical
Wnt signaling by
Wnt10b inhibits differentiation of preadipocytes in vitro
Bennett et al., Proc Natl Acad Sci U S A 2005
:
Activation of
Wnt signaling by
Wnt10b inhibits differentiation of preadipocytes and blocks adipose tissue development ; however, the effect of Wnt10b on other mesenchymal lineages has not been defined
Platt et al., J Nutr Biochem 2009
:
Osteoblast differentiation from MSCs requires
activation of
Wnt/beta-catenin signaling by
Wnt10b , which inhibits adipocyte differentiation by suppressing CCAAT/enhancer binding protein (C/EBP) alpha
Terauchi et al., Cell Metab 2009
:
Here, we show that iPTH increases the production of
Wnt10b by bone marrow CD8+ T cells and
induces these lymphocytes to activate canonical
Wnt signaling in preosteoblasts
Abiola et al., PloS one 2009
(MAP Kinase Signaling System) :
Activation of
Wnt/beta-catenin signaling
increases insulin sensitivity through a reciprocal regulation of
Wnt10b and SREBP-1c in skeletal muscle cells
Mödder et al., J Cell Biochem 2011
(Bone Neoplasms...) :
Wnt10b activates the
Wnt , notch, and NF?B pathways in U2OS osteosarcoma cells
Wen et al., Biomaterials 2011
:
Wnt10b mediated activation of canonical
Wnt signaling has been shown to regulate mesenchymal stem cell fate
Mödder et al., J Cell Biochem 2012
(Wnt Signaling Pathway) :
Furthermore, expression of NERKI abrogated
Wnt10b dependent
Wnt activation using a lentiviral mediated reporter assay
Ye et al., International journal of medical sciences 2013
(Wnt Signaling Pathway) :
Previous research has revealed that
Wnt10b activates canonical
Wnt signaling, which is integral to melanocyte differentiation in hair follicles ( HFs )