◀ Back to RAC3
NFKB1 — RAC3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Huttunen et al., J Biol Chem 1999
(Neuroblastoma) :
In contrast, the activation of
NF-kappaB is
inhibited by dominant negative Ras but not
Rac or Cdc42
Werbajh et al., FEBS Lett 2000
:
Here we report a
role for the nuclear receptor coactivator
RAC3 , in modulating
NF-kappa B transactivation
Cammarano et al., J Biol Chem 2001
:
Here we show that although Dbl activation of
NF kappa B requires Cdc42,
Rac , and Rho, the different GTPases activate NF kappa B by different mechanisms
Wroblewski et al., J Cell Sci 2003
(Neoplasm Invasiveness) :
RhoA acted through activation of both NF-kappaB and AP-1, whereas
Rac activated
NF-kappaB but not AP-1
Alvarado et al., Medicina (B Aires) 2011
:
The treatment of HEK293 cells with TNF-a induced an increase in the protein levels of
RAC3 and this was
blocked by an
NF-kB specific inhibitor, suggesting that this transcription factor is involved in the cytokine effect