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NFKB1 — WT1

Text-mined interactions from Literome

Chen et al., Gene Expr 2000 (Wilms Tumor) : Because the human WT1 promoter contains a conserved NF-kappaB site, we investigated whether NF-kappaB also regulates the expression of the human WT1 gene ... We activated NF-kappaB through cytokine stimulation or inhibited NF-kappaB through expression of a NF-kappaB `` super repressor '' in WT1 expressing Wilms tumor, renal carcinoma, and erythroleukemia cultures and examined the level of endogenous WT1 gene expression ... We conclude that despite the presence of conserved NF-kappaB elements in the murine and human WT1 promoters, NF-kappaB is not required to regulate the expression of the WT1 gene in its natural context
Dehbi et al., Oncogene 1998 : Activation of the wt1 Wilms ' tumor suppressor gene by NF-kappaB