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MAPK1 — NEUROD1
Text-mined interactions from Literome
Yamashita et al., J Biol Chem 2000
:
Thus, co-activation of Rap1 by CalDAG-GEFIII apparently attenuated
Ras-MAPK dependent
neuronal differentiation and cellular transformation
Hansen et al., J Neurochem 2000
:
The results indicate that p38
MAPK is a downstream target of the cAMP signaling pathway and that p38 MAPK
plays a key role in
neuronal differentiation induced by cAMP and growth factors by integration of signals from both pathways
Taraviras et al., Eur J Cell Biol 2002
(MAP Kinase Signaling System) :
Epinephrine
induced neuronal differentiation of PC12alpha2 cells through alpha2-AR activation in a subtype dependent manner, internalization of all human alpha2-AR subtypes, and activation of
mitogen activated protein kinase ( MAPK ) and the serine-threonine protein kinase Akt
Kutcher et al., Am J Physiol Cell Physiol 2003
(MAP Kinase Signaling System) :
Inhibition of
neuronal differentiation by nuclear CaMKII was
independent of
MAPK signaling, as sustained Erk phosphorylation was not affected
Li et al., Dev Growth Differ 2006
(MAP Kinase Signaling System) :
Role of
ERK 1/2 signaling in
neuronal differentiation of cultured embryonic stem cells
Yang et al., J Biol Chem 2008
(MAP Kinase Signaling System) :
Basic fibroblast growth factor induced
neuronal differentiation of mouse bone marrow stromal cells
requires FGFR-1,
MAPK/ERK , and transcription factor AP-1 ... Moreover, we have shown that the
mitogen activated protein kinase ( ERK1/2 ) is persistently activated and blockage of ERK activity with the ERK-specific inhibitor U0126
prevents neuronal differentiation
Wang et al., Neurosci Lett 2009
:
Erk1/2 promotes proliferation and
inhibits neuronal differentiation of neural stem cells
Li et al., Chembiochem 2011
:
Taken together, our findings suggest that baicalin induces
neuronal differentiation of C17.2 neural stem cells and that this is
mediated by activation of
Erk1/2
Kim et al., J Biol Chem 1997
:
We further examined the
role of
mitogen activated protein kinase activation in IGF-I stimulated
neuronal differentiation using the mitogen activated protein kinase/ERK kinase inhibitor PD98059
Yao et al., J Biol Chem 1998
:
Induction of
neuronal differentiation of the rat pheochromocytoma cell line, PC12 cells, by nerve growth factor (NGF)
requires activation of the
mitogen activated protein ( MAP ) kinase or extracellular signal regulated kinase ( ERK )