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IRF6 — TGFB3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Hu et al., J Leukoc Biol 1999
:
Anti-inflammatory cytokines, IL-10, and
transforming growth factor ( TGF ) -beta sequentially
inhibited LPS- and cytokine induced microglial cell NF-kappaB activation, RANTES mRNA expression, and protein release
Ayache et al., Osteoarthritis Cartilage 2002
(Osteoarthritis, Knee) :
TGFbeta3 mRNA level was markedly
reduced by
LPS alone, or with both L-NMMA and NAC
Lieb et al., Neurochem Int 2003
(Multiple Sclerosis) :
Among the substances tested, the glucocorticoids prednisone, hydrocortisone, dexamethasone and progesterone as well as
transforming growth factor-beta ( TGF-beta ) dose-dependently
inhibited LPS induced nitric oxide synthase (iNOS) and NO synthesis
MartÃn-Sanz et al., Br J Pharmacol 1998
:
Also,
transforming growth factor-beta inhibited the
LPS- and pro-inflammatory cytokines dependent expression of COX-2