Jin et al., J Leukoc Biol 2013
:
Systemic administration of TLR3 agonist induces IL-7 expression and IL-7 dependent CXCR3 ligand production in the lung
Schmitz et al., Brain Behav Immun 2013
:
Oppositely, CXCR3-deficiency had no protective effect after traumatic nerve injury but reduced EAE evoked hyperalgesia and was associated with reduced clinical EAE scores, a reduction of the pro-inflammatory cell infiltration and reduced upregulation of interferon gamma and interleukin-17 in the spinal cord
Jin et al., Arthritis Rheum 2013
(Autoimmune Diseases...) :
IL-7 plays a pivotal pathogenic role in SS, which is underpinned by an enhanced Th1 response and IFN?/CXCR3 ligand mediated lymphocyte infiltration of target organs