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IL6 — TNFSF10
Text-mined interactions from Literome
Mühlenbeck et al., J Biol Chem 2000
:
Moreover, in these cell lines
interleukin-6 secretion and NF-kappaB activation were
induced by cross linked or non-cross linked
anti-TRAIL , as well as by both receptor-specific IgGs
Choi et al., J Immunol 1999
:
Our data demonstrated that : 1 ) FasL is expressed constitutively on astrocytes taken from a fetus or an adult and that its expression increases when these cells are treated with IL-1, IL-6, or TNF-alpha in which the pretreatment of IFN-gamma triggers astrocytes to express more FasL ; 2 ) astrocytes induce apoptosis in MOLT-4 cells through FasL ; 3 ) Fas is also expressed constitutively and is up-regulated by IL-1,
IL-6 , or TNF-alpha in which the pretreatment of IFN-gamma triggers astrocytes to express more Fas ; 4 ) apoptosis occurs when fetal astrocytes are treated with agonistic anti-Fas IgM Ab after culture with IFN-gamma and TNF-alpha ; and 5 )
TNF related apoptosis inducing ligand is
up-regulated in fetal astrocytes with stimuli of IL-1 or TNF-alpha