Gene interactions and pathways from curated databases and text-mining

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IL6 — LTF

Text-mined interactions from Literome

Zimecki et al., Arch Immunol Ther Exp (Warsz) 1999 : Lactoferrin increases the output of neutrophil precursors and attenuates the spontaneous production of TNF-alpha and IL-6 by peripheral blood cells
Zimecki et al., Inflamm Res 2003 (Jaundice, Obstructive) : The aim of this study was to evaluate effects of bovine lactoferrin ( BLF ) on histopathological changes in the liver of 14 day obstructive jaundiced ( OJ ) rats and production of tumor necrosis factor ( TNF-alpha ) and interleukin 6 (IL-6) by splenocytes from 7- and 14-day OJ rats
Griffiths et al., Dig Dis Sci 2004 : Neither bifidobacteria nor lactoferrin stimulated an increase in B or T cells, or in cytokine production ( IL-6 , TNF-alpha, INF-gamma ), in Peyer 's patches as measured by flow cytometry
Artym et al., J Chemother 2004 (Disease Models, Animal) : Effects of lactoferrin on IL-6 production by peritoneal and alveolar cells in cyclophosphamide treated mice
Machnicki et al., Int J Exp Pathol 1993 : Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo
Machnicki et al., Postepy Hig Med Dosw 1995 : Moreover, lactoferrin induces by itself relatively high level of IL-6 , peaking at 1 h following injection
Mattsby-Baltzer et al., Pediatr Res 1996 : Lactoferrin or a fragment thereof inhibits the endotoxin induced interleukin-6 response in human monocytic cells
Zimecki et al., Arch Immunol Ther Exp (Warsz) 1998 (Postoperative Complications...) : Bovine lactoferrin ( BLF ; 10 mg/mouse ), given intravenously ( i.v. ) 24 h before thymectomy, reduced , on average, the level of serum IL-6 by 70 % as measured 4 h after operation
Adamik et al., Arch Immunol Ther Exp (Warsz) 1998 (Critical Illness...) : We studied the effect of lactoferrin (LF) on the proliferative response of peripheral blood mononuclear cells ( PBMC ) to lipopolisaccharide (LPS) in vitro and its influence on production of 2 proinflammatory cytokines : interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha) ... Lactoferrin alone was a good inducer of IL-6 and TNF-alpha production by monoclear cells in vitro ... Lactoferrin is a good inducer of IL-6 and TNF-alpha production