Gene interactions and pathways from curated databases and text-mining

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IFNG — TNFRSF11A

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: IFNG → TNFRSF11A (increases) Yu et al., J Immunol 2003*
    Evidence: Treatment of immature monocyte-derived dendritic cells (iMDDCs) with a combination of all three TNF family molecules did not always enhance CTL responses (activity was measured by checking the increase in intracellular IFN gamma production) above those with CD40LT treatment alone. Thus, CD40LT, TNF-alpha, or RANKLT conditioning of iMDDCs could expand HIV-1-specific memory CTL with the greatest expansions observed with CD40LT.