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IFNG — LTB

Text-mined interactions from Literome

Montero et al., Exp Nephrol 2000 (Glomerulonephritis) : When LTB ( 4 ) release was measured, both IL-1 beta and interferon-gamma significantly increased LTB ( 4 ) production by monocytes, while TH-2 cytokines ( IL-4 and IL-13 ) decreased it
Antonelli et al., J Biol Regul Homeost Agents 1990 : To test the involvement of PGE2 and LTB4 in IFN-gamma production, GO- and SEB activated PBMC were treated with two inhibitors of cyclooxygenase ( aspirin and indomethacin ) and with an inhibitor of lipoxygenase [ nordihydroguaiaretic acid ( NDGA ) ]
Rola-Pleszczynski et al., Prostaglandins Leukot Med 1986 : Interleukin 2 (IL-2) and interferon-gamma (IFN) production by human lymphocytes was significantly enhanced in the presence of leukotriene B4 (LTB4) and indomethacin
Ito et al., Immunology 1987 : Meanwhile, IFN-gamma did not affect the production of LTB4 and PGE2
Rola-Pleszczynski et al., J Immunol 1987 : These results suggest that LTB4 may regulate immune cell functions by inducing IFN-gamma production by T4+ cells
Arcoleo et al., Int J Immunopharmacol 1995 : However, LTB4 augmented ConA spleen cell production of interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) from Th1 cells and interleukin-4 (IL-4) and interleukin-10 (IL-10) from Th2 cells more than the controls treated with ConA alone