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FOXP3 — LIF
Text-mined interactions from Literome
Muthukumarana et al., Int Immunopharmacol 2006
(Graft vs Host Disease) :
In spleen cells from allo rejected mice we found that exogenous LIF reduced interferon gamma release in response to donor antigen by 50 %, but
LIF had no direct effect on levels of
Foxp3 protein in allo primed cells that were either tolerant, or aggressive, for donor antigen
Muthukumarana et al., Transplantation 2007
:
We compared the
effect of
wt-Foxp3 versus mutant DeltaE251-Foxp3, which lacks transcriptional activity, on transcript levels of axotrophin,
LIF , and suppressor of cytokine signaling-3 ( SOCS-3 ; a feedback inhibitor of LIF ) in the Jurkat human T-cell line