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EGF — FLNA

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: FLNA → EGF (increases) Olsen et al., Cell 2006*
  Evidence: We have detected 6,600 phosphorylation sites on 2,244 proteins and have determined their temporal dynamics after stimulating HeLa cells with epidermal growth factor (EGF) and recorded them in the Phosida database

Text-mined interactions from Literome

Woo et al., Mol Cell Biol 2004 (MAP Kinase Signaling System...) : Inhibition of MAP kinase signaling with UO126 or mutation of Ser ( 2152 ) to Ala on FLNa prevents epidermal growth factor (EGF) stimulated phosphorylation of FLNa in vivo
Fiori et al., Endocrinology 2009 (Melanoma) : However, it is unclear whether FLNa regulates the signaling capacity and/or down-regulation of the activated epidermal growth factor receptor (EGFR)
Vial et al., J Biol Chem 2012 : EGF mediated FLNa phosphorylation was completely blocked by an inhibitor of p90RSK and partially attenuated by an inhibitor of Rho kinase, suggesting that both pathways converge on FLNa to regulate integrin function