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CSN2 — EGF

Text-mined interactions from Literome

Benton et al., Endocrinology 1999 : Culture of primary rat mammary epithelial cells ( RMEC ) under lactogenic conditions revealed that expression of beta-casein was independent of epidermal growth factor (EGF) in RMEC from virgin WKYv, but was dependent in WFv, RMEC
Galbaugh et al., BMC cell biology 2006 : The expression of CA-Akt inhibited lactogenic differentiation of HC11 cells, and the infection with DN-Akt adenovirus enhanced beta-casein transcription and rescued beta-casein promotor regulated luciferase activity in the presence of EGF
Ackerman et al., J Biol Chem 1989 : Regulation of casein kinase II activity by epidermal growth factor in human A-431 carcinoma cells
Arakawa et al., Exp Cell Res 1985 : Epidermal growth factor (EGF) inhibited casein production and the accumulation of casein mRNA activity induced by insulin (I), cortisol ( F ) and prolactin (P) in a primary culture of mammary epithelial cells from pregnant mice ... Dibutyryl cyclic AMP ( db-cAMP ), cAMP, and 3-isobutylmethylxanthine ( IBMX ), an inhibitor of phosphodiesterase, also antagonized the inhibitory effect of EGF on casein production ... These results suggest a possible modulatory role of cAMP in EGF induced inhibition of casein production in cultured mammary epithelial cells
Sankaran et al., Biochem Biophys Res Commun 1987 : It has been observed that EGF inhibits the induction of casein synthesis by mouse mammary tissue in vitro in addition to acting as a promoter of mammary epithelial proliferation ... The current studies demonstrate, in fact, that EGF inhibits the induction of casein synthesis in vitro only when insulin is present in the culture medium at unphysiologically high concentrations
Komura et al., Endocrinology 1986 : EGF inhibited the synthesis of casein and decreased alpha-lactalbumin activity of mammary explants in culture in the presence of insulin, cortisol, and PRL ... Concomitant addition of retinoic acid with EGF had no significant effect on EGF induced inhibition of casein synthesis, but enhanced EGF induced inhibition of alpha-lactalbumin activity dose dependently
Taketani et al., Endocrinology 1983 : In contrast, EGF inhibited hormonal induction of the synthesis of casein and alpha-lactalbumin in those cells by about 45 % and 55 %, respectively, without inhibiting total protein synthesis
Darcy et al., J Cell Physiol 1995 : Prolactin ( 0.01-10 micrograms/ml ) and EGF ( 1-100 ng/ml ) were each required for induction of cell growth, extensive alveolar, as well as multilobular branching morphogenesis, and casein accumulation
Nishikawa et al., Am J Physiol 1994 : Progesterone and EGF inhibit mouse mammary gland prolactin receptor and beta-casein gene expression