Gene interactions and pathways from curated databases and text-mining

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CSN3 — TP53

Text-mined interactions from Literome

Yoneda-Kato et al., EMBO J 2005 (Leukemia, Myeloid) : A reduction in the level of CSN3 protein with small interfering RNA abrogated MLF1 induced G1 arrest and impaired the activation of p53 by genotoxic stress
Zhang et al., J Cell Biochem 2008 : Roles for CSN5 in control of p53/MDM2 activities ... CSN5 expression leads to p53 degradation, facilitating MDM2 mediated p53 ubiquitination, and promoting p53 nuclear export
Fritsche et al., Mol Cell Endocrinol 1998 : p53 repressed the prolactin induction of the Stat5 mediated transcription of the beta-casein promoter-luciferase reporter gene, but did not affect IFN-gamma induced, Stat1 dependent transcription of the IRF-1 promoter