Gene interactions and pathways from curated databases and text-mining

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CD4 — TNFSF9

Text-mined interactions from Literome

Gramaglia et al., Eur J Immunol 2000 : Blocking studies with activated B cells presenting antigen showed that 4-1BB participates in promoting IL-2 production by resting CD4 cells, confirming that 4-1BBL can play a role in antigen-specific CD4 T cell responses
Blazar et al., J Immunol 2001 (Graft vs Host Disease...) : By quantifying graft-vs-host disease alloresponses in vivo, we demonstrate that both CD4 ( + ) and CD8 ( + ) T cell mediated alloresponses are regulated by 4-1BB/4-1BB ligand interactions to approximately the same extent
Wen et al., J Immunol 2002 : However, murine 4-1BBL can stimulate both CD4 and CD8 T cells ... To further understand the role of 4-1BBL in human T cell responses, we compared human CD4 and CD8 T cell responses to transfected human 4-1BBL plus TCR mediated stimulation
Dawicki et al., Eur J Immunol 2004 : To clarify the role of 4-1BB/4-1BBL in CD4+ versus CD8+ T cell responses in vivo, we compared CD4 ( OT-II ) and CD8 ( OT-I ) TCR transgenic T cells responding to the same antigen in an in vivo adoptive transfer model in 4-1BBL ( +/+ ) versus 4-1BBL ( -/- ) mice