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PRR4 — RAD51
Text-mined interactions from Literome
Gangavarapu et al., Mol Cell Biol 2006
:
In contrast to the
role of
Rad5 in
PRR , however, where its function is coupled with that of Mms2-Ubc13, Rad5 function in TLS would be largely independent of this ubiquitin conjugating enzyme complex
Zhao et al., Mol Cell 2007
:
The ubiquitin ( Ub ) -conjugating enzyme Ubc13 is implicated in
Rad6/Rad18 dependent
postreplication repair ( PRR ) in budding yeast, but its function in vertebrates is not known
McIntyre et al., Curr Genet 2007
:
The same similarity has previously been reported for yeast deficient in Mms2, a protein involved in
Rad6 dependent
postreplication DNA repair ( PRR )
Pagès et al., Genetics 2008
:
In yeast, Rad6-Rad18 dependent lesion bypass involves translesion synthesis ( TLS ) by DNA polymerases eta or zeta or
Rad5 dependent
postreplication repair ( PRR ) in which error-free replication through the DNA lesion occurs by template switching
Hishida et al., Mol Cell Biol 2010
:
Previously it was shown that the loss of
RAD6 dependent error-free
postreplication repair ( PRR ) results in DNA damage checkpoint mediated G ( 2 ) arrest in cells exposed to chronic low-dose UV radiation ( CLUV ), whereas wild-type and nucleotide excision repair-deficient cells are largely unaffected
Kozhina et al., Genetika 2012
:
Genetic studies on a yeast Saccharomyces cerevisiae model showed that the initial stage of
postreplication repair ( PRR ) , i.e., initiation of replication through DNA damage, is
controlled by
Rad6-Rad18 ubiquitin conjugating enzyme complex