◀ Back to TLR8
IDO1 — TLR8
Text-mined interactions from Literome
Furset et al., Immunology 2008
:
Here we show that the activation of
Toll-like receptors (TLR)-7/8 with isRNAs or R848, a specific ligand for TLR7/8, can
induce IDO expression in human monocytes, but not in monocyte derived dendritic cells ( moDC )
Opitz et al., Stem Cells 2009
:
Induction of
IDO1 by
TLR involved an autocrine interferon (IFN)-beta signaling loop, which was dependent on protein kinase R (PKR), but independent of IFN-gamma
Park et al., Exp Mol Med 2011
(Arthritis, Rheumatoid) :
Surprisingly,
toll-like receptor (TLR)4 mediated
IDO expression was upregulated after depletion of myeloid differentiation primary response protein 88 ( MyD88 ) in synovial fibroblasts using small interfering RNA ( siRNA )
Lei et al., J Med Primatol 2013
:
Toll-like receptor ( TLR ) stimulation significantly
increased IDO protein level in CD14 ( + ), CD56 ( + ), CD1c ( + ), CD11c ( + ), and CD123 ( + ) myeloid cells