Hu et al., J Immunol 2003
:
We investigated whether GCs could also block activation of Janus kinase-STAT signaling by IFN-gamma, a potent proinflammatory cytokine
Ishida-Takahashi et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
To clarify the molecular mechanism by which GCs rapidly reduce leptin induced JAK/STAT signaling, we examined the intracellular signal transduction pathway potentially mediated by GCs ... PD98059, a specific MEK inhibitor, blocked the inhibitory effects of GCs on leptin induced JAK/STAT activation in Huh7 cells