Gene interactions and pathways from curated databases and text-mining

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RELA — TMED7

Text-mined interactions from Literome

Chandramohan et al., J Immunol 2004 : B cell receptor (BCR) engagement of murine WEHI 231 immature B lymphoma cells leads sequentially to a drop in NF-kappa B and c-Myc, and induction of the p27 ( Kip1 ) cyclin dependent kinase inhibitor, which promotes growth arrest and apoptosis
Nasr et al., Oncogene 2005 (Leukemia-Lymphoma, Adult T-Cell...) : PS-341 treatment of these cells stabilized IkappaBalpha, IkappaBbeta, IkappaBvarepsilon, p21, p27 and p53 proteins and selectively inhibited Rel-A DNA binding NF-kappaB complexes
Lee et al., American journal of physiology. Renal physiology 2008 : Consequently, the inhibition of Ca ( 2+ ), PKC, EGFR, p44/42 MAPKs, or NF-kappaB blocked the BSA induced increases in cyclin D1, cyclin dependent kinase (CDK)4, cyclin E, or CDK2 and restored the BSA induced inhibition of p21 ( WAF/Cip1 ) and p27 ( Kip1 ) expression
Shankar et al., Molecular cancer 2008 (Neoplasm Metastasis...) : In xenogrfated tumors, curcumin upregulated the expression of TRAIL-R1/DR4, TRAIL-R2/DR5, Bax, Bak, p21/WAF1, and p27/KIP1 , and inhibited the activation of NFkappaB and its gene products such as cyclin D1, VEGF, uPA, MMP-2, MMP-9, Bcl-2 and Bcl-XL