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GGT1 — RELA
Text-mined interactions from Literome
Maellaro et al., J Cell Sci 2000
(Melanoma) :
In addition,
GGT expression
results in an up-regulation of the transcription factor
NF-kappa B , which could explain the higher metastatic behaviour reported for GGT-rich melanoma cells as compared to their GGT-poor counterparts
Djavaheri-Mergny et al., Mol Cell Biochem 2002
:
Moreover, we show that lipid peroxidation is involved in GGT dependent NF-kappaB activation since vitamin E, which completely inhibits GGT induced generation of lipid peroxides, prevents the
GGT dependent
NF-kappaB activation ... This finding suggests that
GGT mediated
NF-kappaB activation plays a role in the control of apoptosis in U937 cells