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PAK1 — TNF
Text-mined interactions from Literome
Kettritz et al., J Am Soc Nephrol 2002
:
TNF-alpha stimulation
increased association of
PAK1 with Akt
Zhou et al., BMC immunology 2009
:
In
response to
TNF-alpha or IL-1alpha,
PAK1 was promptly activated, as characterized by a sequential phosphorylation, initiated at threonine-212 followed by at threonine-423 in the activation loop of the kinase, in human skin keratinocytes, dermal fibroblasts, and rat hepatic stellate cells
Park et al., Am J Physiol Lung Cell Mol Physiol 2012
:
These combined data are consistent with the hypothesis that PPAR? stimulates MUC1/Muc1 expression, thereby blocking
PMA/PAK induced
TNF-a/IL-8 production by airway epithelial cells