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GAP43 — NEUROD2
Text-mined interactions from Literome
Mani et al., Brain Res 2000
:
Targeted disruption of
GAP-43 in P19 embryonal carcinoma cells
inhibits neuronal differentiation
Van Lookeren Campagne et al., J Neurocytol 1989
:
Accumulating evidence indicates that the neuron-specific
B-50/GAP43 , a substrate for protein kinase C,
plays a role in
neuronal differentiation and neuritogenesis during nervous tissue development and axonal regeneration
Shea et al., J Neurosci Res 1995
(Neuroblastoma) :
These results are in conformity with recent studies showing that the requirement for GAP-43 in neuritogenesis may be related to membrane adhesiveness, and may contribute to an understanding of some of the apparent discrepancies in the literature concerning the
involvement of
GAP-43 in
neuronal differentiation
Kumagai-Tohda et al., J Neurochem 1993
:
Thus,
GAP-43 may be
involved in
neuronal differentiation in NG108-15 cells
McCormick et al., Mol Cell Biol 1996
:
Transfection of vectors expressing neuroD and neuroD2 into P19 cells shows that both can activate expression through simple E-box-driven reporter constructs and can activate a reporter driven by the neuroD2 promoter region, but the
GAP-43 promoter is preferentially
activated by
neuroD2