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MAPK12 — ODC1

Text-mined interactions from Literome

Flamigni et al., Biochem J 1999 (Leukemia, Experimental) : In d, l-alpha-difluoromethylornithine ( DFMO ) -resistant L1210 cells stimulated to grow from quiescence, treatment with PD98059 inhibited p44/42 MAPK phosphorylation and the induction of ODC activity and protein
Flamigni et al., Biochem Pharmacol 2001 (MAP Kinase Signaling System) : The involvement of p44/42 MAPK and p38 MAPK in the induction of ODC was investigated by using selective inhibitors ... These results show that the p44/42 MAPK pathway, but not p38 MAPK , is essential for ODC induction stimulated either by agonists of G-protein coupled receptors, phorbol esters, or serum, and suggest that the inhibition of ODC induction may be an important event in the antiproliferative response to p44/42 MAPK pathway inhibitors
Kubota et al., J Natl Cancer Inst 1997 (Cell Transformation, Neoplastic...) : Our purpose was twofold : 1 ) to determine whether ODC overexpression is directly involved in tumor cell invasion and 2 ) to determine whether ODC overexpression induces mitogen activated protein ( MAP ) kinase activities that are associated with cell growth and transformation
Shantz et al., Cancer Res 1998 (Cell Transformation, Neoplastic) : Furthermore, expression of the ODC dominant negative mutant did not affect the phosphorylation of mitogen activated protein kinase in nu-Raf transformed cells