Gene interactions and pathways from curated databases and text-mining

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CCL2 — JAK3

Text-mined interactions from Literome

Voss et al., Inflamm Allergy Drug Targets 2012 : While poly ( I:C ) induced IL-8 gene expression was solely inhibited by the NF-?B inhibitor III, MCP-1 gene induction was also blocked by PKA, p38 MAPK and JAK-STAT inhibitors
Pattison et al., FEBS Lett 2013 : Blocking IFNß signaling with Ruxolitinib, a JAK inhibitor, inhibited MCP-1 transcription