Gene interactions and pathways from curated databases and text-mining

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IRF6 — RHOB

Text-mined interactions from Literome

Kamon et al., EMBO J 2006 : LPS increased the activity of RhoB , but not of RhoA, Cdc42, or Rac1/2 in a manor dependent on LPS-TRIF- but not LPS-Myd88 signaling ... Moreover, we found GEFH1 associated with RhoB, and DN-GEFH1 or GEFH1 's RNAi suppressed the LPS mediated RhoB activation and MHCII surface expression
Wang et al., J Physiol Biochem 2013 (Inflammation) : The upregulation of RhoB by LPS was also observed in mouse peritoneal macrophages and in mouse lung, liver, and kidney ... These results demonstrated that LPS induced RhoB expression in mouse in vivo and in vitro and in RAW264.7 cells, and the role of RhoB on LPS induced secretion of TNF-a and NO was at least partly mediated via NF-?B