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IRF6 — MYLIP
Text-mined interactions from Literome
Tili et al., J Immunol 2007
(Shock, Septic) :
LPS stimulation of mouse Raw 264.7 macrophages
resulted in the up-regulation of
miR-155 and down-regulation of miR-125b levels ... Altogether, our data suggest that the
LPS/TNF-alpha dependent regulation of miR-155 and
miR-125b may be implicated in the response to endotoxin shock, thus offering new targets for drug design
Bazzoni et al., Proc Natl Acad Sci U S A 2009
(Inflammation) :
Among the 3 different genes encoding miR-9 precursors in humans, we show that
LPS selectively
induces the transcription of
miR-9-1 located in the CROC4 locus, in a MyD88- and NF-kappaB dependent manner
Schmelzer et al., Mediators Inflamm 2009
:
Preincubation of human monocytic THP-1 cells with ubiquinol-10 reduced the
LPS induced expression level of
miR-146a to 78.9 +/- 13.22 % ... In liver samples of mice injected with LPS, supplementation with ubiquinol-10 leads to a reduction of
LPS induced
miR-146a expression to 78.12 +/- 21.25 %
Jennewein et al., J Biol Chem 2010
:
We provide evidence that
LPS induced
miR-27b contributes to destabilization of PPARgamma1 mRNA
Murphy et al., J Immunol 2010
:
LPS induces let-7a and
inhibits miR-125b expression in human macrophages, and pretreatment with estradiol abrogates these effects
Tili et al., Carcinogenesis 2010
:
Finally, we show that resveratrol impairs the
upregulation of
miR-155 by
LPS in a miR-663 dependent manner
Roderburg et al., Hepatology 2011
(Carbon Tetrachloride Poisoning...) :
On a cellular level, down-regulation of
miR-29 in murine hepatic stellate cells ( HSCs ) was
mediated by transforming growth factor beta ( TGF-ß ) as well as inflammatory signals, namely,
lipopolysaccharide (LPS) and nuclear factor kappa B ( NF-?B )
Thompson et al., J Biol Chem 2011
(Lymphoma, Large B-Cell, Diffuse) :
Additionally,
miR-155 is
induced by
LPS treatment or expression of the CARD11 mutant in BJAB cells
Jiang et al., Cell Biochem Funct 2011
:
These results suggested that the expression of
miR-17-3p and miR-106a is
regulated by TNFa and
LPS in HeLa cells
Hennessy et al., J Biol Chem 2011
:
We have therefore identified a mechanism for
LPS signaling which
involves a decrease in
miR-107 leading to an increase in CDK6
Zhou et al., PloS one 2012
(MAP Kinase Signaling System) :
LPS stimulation
activated miR-16 gene transcription in human monocytes ( U937 ) and biliary epithelial cells ( H69 ) through MAPK dependent mechanisms
Zeng et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2012
:
To study the effects of Shenfu injection ( SF ) on the expression of
lipopolysaccharide(LPS) induced
microRNA-146a (miR-146a) in rat alveolar macrophages ( AMs ), and to extrapolate its potential anti-inflammatory mechanisms
Nahid et al., J Immunol 2013
:
During bacterial infection, PGN mediated TLR2 signaling induces miR-132/-212 to downregulate IRAK4, an early component in the MyD88 dependent pathway, whereas
LPS/TLR4 induced
miR-146a downregulates downstream components of the same MyD88 dependent pathway
Xue et al., Placenta 2013
:
Here we demonstrated that
miR-155* ,
induced by
lipopolysaccharide (LPS) in an AP-1/NF-?B dependent manner, played a positive feedback role in AP-1/NF-?B pathway via targeting interleukin-1 receptor associated kinase M ( IRAKM ) and NF-?B inhibitor interacting Ras-like 1 ( NKIRAS1 ) in trophoblasts
Lee et al., Oncogenesis 2013
:
In conclusion, our study for the first time reveals the contribution of miR-26a-2 to LPS tumorigenesis, partly through inhibiting RCBTB1, suggesting that
miR-26a-2 is a novel therapeutic
target for human
LPS
Zhou et al., PloS one 2013
:
Induction of CX3CL1 and downregulation of
miR-424 and miR-503 were also detected in epithelial cells in
response to
LPS stimulation
Olivieri et al., Free Radic Biol Med 2013
(Inflammation) :
However, short-term CoQ10H2 supplementation attenuated LPS induced MIRAKIL changes in young cells ; in senescent cells CoQ10H2 supplementation significantly attenuated
LPS induced
miR-146a and IRAK-1 modulation but failed to curb IL-6 release