◀ Back to GPI

GPI — IL4

Text-mined interactions from Literome

Gratchev et al., Skin Pharmacol Appl Skin Physiol 2001 (Skin Diseases) : Among polarized APC, effector macrophages are classically activated by mediators such as IFN-gamma, TNF-alpha or LPS ( M phi 1 ), while M phi 2 are alternatively activated by IL-4 , IL-10 or PGE ( 2 )
Jaffar et al., J Immunol 2007 (Asthma...) : In vitro studies showed that PGI ( 2 ) did not affect IL-4 and IL-5 production or the level of IFN-gamma by the T cells
von Kleist et al., Immunobiology 1990 : LPS, IL6, and IL4 caused induction of up to 15 % Fo+ and Ia+ M phi after a 4 d culture period
Marcinkiewicz et al., Cell Immunol 1993 : Unexpectedly, IL-4 release was strongly inhibited by exogenous PGI2 , while remaining unaffected by PGE2
Chakkalath et al., J Immunol 1994 : Results indicated that L. major infected M phi enhanced the proliferation and IL-4 secretion of Th2 T cells in response to stimulation with their cognate Ag
Sasaki et al., Blood 1997 (Hematologic Neoplasms...) : Phorbol 12-myristate 13-acetate ( PMA ), interleukin-1 (IL-1), IL-3, IL-6, granulocyte-macrophage colony stimulating factor ( GM-CSF ), thrombopoietin (TPO), and tumor necrosis factor-alpha (TNF-alpha) enhanced PGI2-R mRNA expression
Kodelja et al., Immunobiology 1997 : However, well characterized M phi subsets such as IFN-gamma induced, classically activated ( ca ) M phi or IL-4/glucocorticoid induced , alternatively activated ( aa ) M phi have not been thoroughly examined for a positive or negative association with angiogenesis