Gene interactions and pathways from curated databases and text-mining

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EDN1 — SRF

Text-mined interactions from Literome

Liu et al., J Biol Chem 2003 : Endothelin ( EDN ) receptor type B ( EDNRB ) activates serum response factor (SRF) via G ( q/11 ) and G ( 12/13 ) G proteins
Marshall et al., PloS one 2010 (Hypertrophy) : RhoA plays a major role in maintaining baseline RNA expression but, with upregulation of Abra/Srf by endothelin-1 , RhoA may regulate changes in RNA expression over longer times