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EDN1 — HLA-B

Text-mined interactions from Literome

Santaniello et al., Tissue Antigens 2006 (Hypertension, Pulmonary...) : HLA-B35 upregulates the production of endothelin-1 in HLA transfected cells : a possible pathogenetic role in pulmonary hypertension
Lenna et al., J Immunol 2010 (Hypertension, Pulmonary) : HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells ... Our data demonstrate that HLA-B35 expression at physiological levels via adenoviral vector resulted in significantly increased endothelin-1 (ET-1) and a significantly decreased endothelial NO synthase (eNOS), mRNA, and protein levels